Human Pulmonary Artery Endothelial Cells

Reference: P10553

Human Pulmonary Artery Endothelial Cells

Human Pulmonary Artery Endothelial Cells (HPAEC) provided by Innoprot are isolated from human healthy lung. HPAEC are cryopreserved at passage one and delivered frozen. Each vial of Human Pulmonary Artery Endothelial Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Pulmonary Artery Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HPAEC culture.


Size/Quantity: 500.000 Cells / vial


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The pulmonary artery carries deoxygenated blood from the heart to the lungs. Similar to other vascular endothelial cells, human pulmonary artery endothelial cells (PAEC) modulate coagulation and fibrinolysis by producing activators and inhibitors of both processes. In addition, PAEC produce mediators that influence the adhesion and aggregation of blood platelets. PAEC also control vascular tone by synthesizing and processing vasoactive molecules. PAEC further interact with mesenchymal cells and regulate inflammatory events. Such functions of PAEC play roles in acute lung injury, pulmonary hypertension, edema, embolism, pulmonary artery aneurysm and chronic obstructive lung disease. HPAEC will provide an in vitro model in the pathophysiological studies of vascular diseases; such pulmonary arterial hypertension. They are also useful tools to stablish in vitro disease models for High Throughput and High Content Screening.

  • Reference: P10553
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice