Human Pulmonary Artery Fibroblasts

Reference: P10555

Human Pulmonary Artery Fibroblasts

Human Pulmonary Artery Fibroblasts (HPAF) provided by Innoprot are isolated from human pulmonary artery. HPAF are cryopreserved at passage one and delivered frozen. Each vial of Human Pulmonary Artery Fibroblasts contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Pulmonary Artery Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HPAF culture.


Size/Quantity: 500.000 Cells / vial


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Fibroblasts are mesenchymal cells which came from the embryonic mesoderm. They are useful for a wide range of cellular and molecular studies as they are one of the easiest types of cells to grow in culture. Their durability also makes them amenable to a variety of manipulations ranging from studies employing gene transfection to microinjection. There is evidence showing that fibroblasts in various organs are intrinsically different. Specifically, human pulmonary artery fibroblasts (HPAF) are important modulators of vascular wall function. During pathological conditions, such as hypoxia-induced pulmonary hypertension, HPAF become proliferative which contributes to adventitial thickening. HPAF play an important role in vascular disease research helping to identify new therapeutic targets to treat pulmonary vascular disease. They are also useful tools to stablish in vitro disease models for High Throughput and High Content Screening.

  • Reference: P10555
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice

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