{"id":1200,"date":"2019-01-13T00:30:28","date_gmt":"2019-01-12T23:30:28","guid":{"rendered":"http:\/\/innoprot.com\/?post_type=product&p=1200"},"modified":"2019-12-12T11:37:39","modified_gmt":"2019-12-12T10:37:39","slug":"neurite-outgrowth-mitosis-assay-cell-line","status":"publish","type":"product","link":"https:\/\/innoprot.com\/es\/producto\/neurite-outgrowth-mitosis-assay-cell-line\/","title":{"rendered":"Neurite Outgrowth & Mitosis Assay Cell Line"},"content":{"rendered":"

Neurite outgrowth is a key process during neurogenesis. During development, neurons extend numerous processes that differentiate into dendrites and axons. These processes, also termed neurites, are critical for communication between neurons.\u00a0 The initiation of neurite protrusion and subsequent elongation involves complex intracellular signaling. Neurites are particularly interesting in relation to neuropathological disorders, neuronal injury\/regeneration, and neuropharmacologic research and screening. Neurite Outgrowth & Mitosis Assay Cell Line allows the analysis of neurites while monitoring the cellular mitosis level through microtubule structural changes.<\/p>\n

The growth of neurites in human neurons is a critical event in neuronal development; formation and remodelling of synapses, response to injury, and regeneration. Many neuroscience projects are focused on identifying new drugs that affect this event. The discovery of new compounds that can positively affect neuritogenesis are very important for developing new therapeutics against both neurodegenerative diseases and injury. Measurement of neurite outgrowth using an automated image-based assay can be of use in the research; screening and validation phases of the drug discovery process.<\/p>\n","protected":false},"excerpt":{"rendered":"

Neurite Outgrowth & Mitosis Assay Cell Line (TagGFP2\u2010Tubulin SH\u2010SY5Y Cell line) allows the analysis of neurites while monitoring the cellular mitosis level through microtubule structural changes. It consists in SH-SY5Y cell line stably expressing green fluorescent tubulin marking the cell cytoskeleton and it can be easly differentiated using standardized protocols to promote the neurite outgrowth.<\/p>\n

Innoprot offers this assay as a \u201cstable cell line\u201d in cryopreserved vials. Each vial of SH-SY5Y cell line stably expressing TagGFP2-tubulin contains 3 million cells. It is guaranteed that these cells will expand in more than 30 passages following the cell culture manual.<\/p>\n","protected":false},"featured_media":1201,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[115],"product_tag":[304,303,301,302],"class_list":["post-1200","product","type-product","status-publish","has-post-thumbnail","product_cat-stable-cell-lines-for-drug-screening-in-cns","product_tag-assay","product_tag-cns","product_tag-meurite-outgrowth","product_tag-mitosis","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"acf":[],"yoast_head":"\nNeurite Outgrowth & Mitosis Assay Cell Line — Innoprot Stable Cell Lines<\/title>\n<meta name=\"description\" content=\"Neurite Outgrowth & Mitosis Assay Cell Line from Innoprot allows the measurement in vitro of the capacity of compounds to induce\/inhibit neurite formation.\" \/>\n<meta name=\"robots\" content=\"index, follow, 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