{"id":1769,"date":"2019-03-04T11:34:18","date_gmt":"2019-03-04T10:34:18","guid":{"rendered":"http:\/\/innoprot.com\/?post_type=product&#038;p=1769"},"modified":"2025-12-01T14:10:36","modified_gmt":"2025-12-01T13:10:36","slug":"green-fluorescent-b2-bradykinin-receptor-cell-line","status":"publish","type":"product","link":"https:\/\/innoprot.com\/es\/producto\/green-fluorescent-b2-bradykinin-receptor-cell-line\/","title":{"rendered":"Green Fluorescent B2 Bradykinin Receptor Cell Line"},"content":{"rendered":"<p>The bradykinin receptor family is a group of G-protein receptors whose principal ligand is the protein bradykinin. This gene encodes a receptor for bradykinin B2. The 9 aa bradykinin peptide elicits many responses such as vasodilation, edema, smooth muscle spasm and pain fiber stimulation. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Classical agonist of this receptor includes bradykinin1-8 (bradykinin with the first 8 amino acid) and antagonist includes [Leu8]-bradykinin1-8. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Green Fluorescent B2 Bradykinin Receptor Cell Line from Innoprot allows the measurement of the activity and potency of ligands; such as bradykinin.<\/p>\n<p>Click <a href=\"http:\/\/www.guidetopharmacology.org\/GRAC\/ObjectDisplayForward?objectId=42&amp;familyId=10&amp;familyType=GPCR\">HERE<\/a> to know more about Bradykinin Receptor B2.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Green Fluorescent GPCR cell lines from Innoprot allows to perform GPCR internalization assays. Each vial of\u00a0<strong>Green Fluorescent B2 Bradykinin Receptor Cell Line<\/strong> contains CHO-K1 cells stably expressing BDKRB2 tagged with tGFP.\u00a0 These Cell lines proliferate in vitro maintaining fluorescent GPCR expression following the cell culture manual.<\/p>\n<p>Innoprot\u00a0<strong>Green Fluorescent B2 Bradykinin Receptor Cell Line<\/strong> allows to assay compounds, or analyze their capability to modulate BDKRB2 activation and the following redistribution process inside the cells. When a ligand binds to the BDKRB2, it activates a G protein, which internalizes in big and high intensity vesicles. This cell line has been validated measuring Fluorescent BDKRB2 redistribution by increase of fluorescence surrounding the nuclei using image analysis algorithms. The high reproducibility of this assay allows monitoring B2 Bradykinin Receptor redistribution process in High Throughput Screening.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Size\/Quantity<\/strong>: 2 vials containing 3&#215;10<sup>6<\/sup> cells \/ vial<\/p>\n","protected":false},"featured_media":1772,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[349],"product_tag":[435,430],"class_list":["post-1769","product","type-product","status-publish","has-post-thumbnail","product_cat-bdkr2","product_tag-bradykinin-receptor","product_tag-gpcr","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Green Fluorescent B2 Bradykinin Receptor Cell Line &#8212; Innoprot Cell Lines<\/title>\n<meta name=\"description\" content=\"Each vial of Green Fluorescent B2 Bradykinin Receptor Cell Line contains 3 million cells CHO-K1 cells stably expressing Green Fluorescent human BDKRB2\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/innoprot.com\/es\/producto\/green-fluorescent-b2-bradykinin-receptor-cell-line\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Green Fluorescent B2 Bradykinin Receptor Cell Line &#8212; 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