{"id":1860,"date":"2019-03-05T23:03:16","date_gmt":"2019-03-05T22:03:16","guid":{"rendered":"http:\/\/innoprot.com\/?post_type=product&p=1860"},"modified":"2025-12-01T14:35:56","modified_gmt":"2025-12-01T13:35:56","slug":"green-fluorescent-fpr2-alx-formylpeptide-receptor-cell-line","status":"publish","type":"product","link":"https:\/\/innoprot.com\/es\/producto\/green-fluorescent-fpr2-alx-formylpeptide-receptor-cell-line\/","title":{"rendered":"Green Fluorescent FPR2\/ALX Formylpeptide Receptor Cell Line"},"content":{"rendered":"

The formyl peptide receptors (FPRs) are GPCRs that transduce chemotactic signals in phagocytes. They mediate host-defense as well as inflammatory responses including cell adhesion, migration, granule release and superoxide production. The FPR2 receptor is present on human neutrophils, eosinophils, monocytes, macrophages, T cells, synovial fibroblasts, and intestinal and airway epithelium. FPR2 is also known as the LXA4 or ALX\/FPR2 receptor based on studies finding that is a high affinity receptor for the arachidonic acid metabolite, lipoxin A4 (LXA4), and thereafter for a related arachidonic acid metabolite, the Epi-lipoxin, aspirin-triggered lipoxin A4 (i.e. ATL, 15-epi-LXA4) and a docosahexaenoic acid metabolite, resolvin D1 (i.e. RvD1); these three cell-derived fatty acid metabolites act to inhibit and resolve inflammatory responses. Green Fluorescent FPR2\/ALX Formylpeptide Receptor Cell Line from Innoprot allows the measurement of the activity and potency of ligands; such as WKYMVm.<\/p>\n

Click HERE<\/a> to know more about FPR2 Receptor.<\/p>\n","protected":false},"excerpt":{"rendered":"

Green Fluorescent GPCR cell lines from Innoprot allows to perform GPCR internalization assays. Each vial of\u00a0Green Fluorescent FPR2\/ALX Formylpeptide Receptor Cell Line<\/strong> contains U2OS cells stably expressing FPR2\/ALX tagged with tGFP. These Cell lines proliferate in vitro maintaining fluorescent GPCR expression following the cell culture manual.<\/p>\n

Innoprot\u00a0Green Fluorescent FPR2\/ALX Formylpeptide Receptor Cell Line<\/strong> allows to assay compounds, or analyze their capability to modulate FPR2\/ALX activation and the following redistribution process inside the cells. When a ligand binds to the FPR2\/ALX Formylpeptide Receptor, it activates a G protein, which internalizes in big and high intensity vesicles. This cell line has been validated measuring Fluorescent FPR2\/ALX redistribution by increase of fluorescence surrounding the nuclei using image analysis algorithms. The high reproducibility of this assay allows monitoring FPR2\/ALX Formylpeptide Receptor redistribution process in High Throughput Screening.<\/p>\n

 <\/p>\n

Size\/Quantity<\/strong>: 2 vials containing 3×106<\/sup> cells \/ vial<\/p>\n","protected":false},"featured_media":1862,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[393],"product_tag":[461,430],"class_list":["post-1860","product","type-product","status-publish","has-post-thumbnail","product_cat-fpr2","product_tag-chemokine-receptor","product_tag-gpcr","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"acf":[],"yoast_head":"\nGreen Fluorescent FPR2\/ALX Formylpeptide Receptor Cell Line — Innoprot<\/title>\n<meta name=\"description\" content=\"Each vial of Green Fluorescent FPR2\/ALX Formylpeptide Receptor Cell Line contains 3 million U2OS cells stably expressing FPR2\/ALX receptor tGFP tagged\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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