{"id":604,"date":"2018-12-05T00:08:12","date_gmt":"2018-12-04T23:08:12","guid":{"rendered":"http:\/\/innoprot.com\/?post_type=product&#038;p=604"},"modified":"2023-01-03T16:23:03","modified_gmt":"2023-01-03T15:23:03","slug":"rat-brain-microvascular-endothelial-cells","status":"publish","type":"product","link":"https:\/\/innoprot.com\/es\/producto\/rat-brain-microvascular-endothelial-cells\/","title":{"rendered":"Rat Brain Microvascular Endothelial Cells"},"content":{"rendered":"<p>Brain microvascular endothelial cells (BMEC), limit the passage of substances, both soluble and cellular, from the blood into the brain. BMEC utilize unique features to distinguish themselves from peripheral endothelial cells, such as; 1) intercellular tight junctions that display high electrical resistance and slow paracellular transport; 2) the absence of fenestrae and a reduced level of pinocytic activity; and 3) the expression of specialized pumps that can transport compounds out of the brain via the blood-brain barrier. Similar to peripheral endothelial cells, BMEC express cell adhesion molecules on their surface that regulate the extravasation of leukocytes into the brain. Rat\u00a0Brain microvascular endothelial cells are useful for studying the molecular and cellular properties of blood-brain barrier. Understanding the molecular mechanisms of blood-brain barrier regulation may help to optimize drug delivery to the CNS and elucidate new therapies for CNS diseases.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rat Brain Microvascular Endothelial cells (RBMEC) provided by Innoprot are isolated from Sprague Dawley rat brain. RBMEC are cryopreserved at passage one and delivered frozen. Each vial of Rat Brain Microvascular Endotheilal Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 10 population doublings following the instructions provided in the technical sheet.<\/p>\n<p>Innoprot also offers optimized medium and reagents for the growth of Rat Brain Microvascular Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro RBMEC culture.<\/p>\n<p><strong>Size\/Quantity:<\/strong> 500.000 Cells \/ vial<\/p>\n","protected":false},"featured_media":4412,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[64],"product_tag":[164,163],"class_list":["post-604","product","type-product","status-publish","has-post-thumbnail","product_cat-neural-cell-system","product_tag-brain-endothelial-cells","product_tag-rat-cells","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Rat Brain Microvascular Endothelial Cells &#8212; 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