Bovine Brain Microvascular Endothelial Cells

Reference: P10338

Bovine Brain Microvascular Endothelial Cells

Bovine Brain Microvascular Endothelial cells (BBMEC) provided by Innoprot are isolated from bovine brain. BBMEC are cryopreserved at passage one and delivered frozen. Each vial of Bovine Brain Microvascular Endotheilal Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 10 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Bovine Brain Microvascular Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro BBMEC culture.

Size/Quantity: 500.000 Cells / vial

750,00

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Brain microvascular endothelial cells (BMEC), limit the passage of substances, both soluble and cellular, from the blood into the brain. BMEC utilize unique features to distinguish themselves from peripheral endothelial cells, such as; 1) intercellular tight junctions that display high electrical resistance and slow paracellular transport; 2) the absence of fenestrae and a reduced level of pinocytic activity; and 3) the expression of specialized pumps that can transport compounds out of the brain via the blood-brain barrier. Similar to peripheral endothelial cells, BMEC express cell adhesion molecules on their surface that regulate the extravasation of leukocytes into the brain. Bovine Brain microvascular endothelial cells are useful for studying the molecular and cellular properties of blood-brain barrier. Understanding the molecular mechanisms of blood-brain barrier regulation may help to optimize drug delivery to the CNS and elucidate new therapies for CNS diseases.

  • Reference: P10338
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice