FluoHiTSeeker FSHR Cell Line

Reference: P30117-F

FluoHiTSeeker FSHR Cell Line

FluoHiTSeeker are cell lines stably co-expressing label-free GPCRs and the CRE-tGFP reporter gene. Each vial of FluoHiTSeeker FSHR Cell Line contains HEK293 cells stably expressing human Follicle Stimulating Hormone Receptor with no tag; and the CRE-tGFP reporter gene as a biosensor to monitor cAMP concentration changes. FluoHiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.

Innoprot FluoHiTSeeker FSHR Cell Line allows to assay compounds, or analyze their capability to modulate FSHR. When a ligand binds to the FSHR, it activates a G protein, which in turn, triggers a cellular response mediated by cAMP. Due to the presence of the CRE-tGFP reporter gene, this cell line allows to monitor cAMP concentration in living cells measuring fluorescence intensity. FluoHiTSeeker FSHR cell line has been validated measuring cAMP concentration changes in the cytosol upon activation with rhFSH. The high reproducibility of this assay allows monitoring FSH receptor activation process in High Throughput Screening.

Size/Quantity: 2 vials containing 3×106 cells / vial


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Follicle stimulating hormone (FSH) is one of the gonadotrophic hormones, as well as luteinising hormone. It regulates the development, growth, pubertal maturation, and reproductive processes of the body. Its activation is necessary for the hormonal functioning of FSH. FSHRs are present in the ovary, tesis and uterus.FSH and luteinizing hormone (LH) work together in the reproductive system. FSH is commonly part in infertility therapies, mainly for ovarian hyperstimulation as part of IVF. In some cases, reversal of anovulation treatments requires FSH as well. FluoHiTSeeker FSHR cell line from Innoprot allows the measurement of the activity and potency of ligands, such as recombinant human FSH (rhFSH).

Click HERE to know more about FSH Receptor.

  • Reference: P30117F
  • 2nd messenger Biosensor: cAMP
  • Size/Quantity: 2 vials containing 3x106 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice