The somatostatin receptor 2 (SSTR2), which belongs to the GPCR family, is a protein which is present in the pancreas, but also in other tissues; such as the cerebrum and kidney and in lower amount in the jejunum, colon and liver. In the pancreas, after binding to somatostatin, it inhibits the secretion of pancreatic enzymes. During development, it stimulates neuronal migration and axon outgrowth. SSTR2 also has the ability to stimulate apoptosis in many cells including cancer cells, converting it in a possible target in cancer treatment for its ability to inhibit tumor growth. Green Fluorescent SST2 Somatostatin Receptor Cell Line from Innoprot allows the measurement of the activity and potency of ligands; such as SST.
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