Human Adrenal Microvascular Endothelial Cells

Reference: P10481

Human Adrenal Microvascular Endothelial Cells

Human Adrenal Microvascular Endothelial cells (HDMEC) provided by Innoprot are isolated from human healthy adrenal tissue. HAdMEC are cryopreserved at passage one and delivered frozen. Each vial of Human Adrenal Microvascular Endotheilal Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Adrenal Microvascular Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HAdMEC culture.

 

Size/Quantity: 500.000 Cells / vial

795,00

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The adrenal gland plays an essential role in regulating homeostasis in the body through the secretion of corticosteroid and androgen hormones. The secreted steroids arise from the three zones of the adrenal gland: the zona glomerulosa, zona fasciculate, and zona reticularis. Microvascular endothelial cells (MEC) line the blood vessels and contribute to many biological processes; such as hemostasis, coagulation, trafficking of lymphocytes, and the inflammatory response. MEC regulate the secretion of adrenal hormones in the adrenal gland. Studies have shown that factors secreted from HAdMEC, such as endothelin-1, nitric oxide, adrenomedullin and proadrenomedullin NH2-terminal 20 peptide affect aldosterone secretion. HAdMEC, unlike brain and liver MECs, are highly resistant to glucocorticoid-induced cytotoxicity. Human Adrenal Microvascular Endothelial Cells are usefull tools for understanding physiological and pathophysiological relevance in adrenal gland function and disease.

  • Reference: P10481
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice