Human Aortic Smooth Muscle Cells

Reference: P10456

Human Aortic Smooth Muscle Cells

Human Aortic Smooth Muscle cells (HASMC) provided by Innoprot are isolated from healthy human aortic tissue. HASMC are cryopreserved at passage one and delivered frozen. Each vial of Human Aortic Smooth Muscle Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Aortic Smooth Muscle Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HASMC culture.

 

Size/Quantity: 500.000 Cells / vial

740,00

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Smooth muscle cells (SMC) are primary contributors to the development of arterial disease. The ability of vascular SMC to switch to a proliferative phenotype is one of the main factors in the development and progression of vascular disease. Recent studies have demonstrated that SMC express calcium channels, ICAM-1, and VCAM-1. The expression of ICAM-1 and VCAM-1 on SMC may contribute to the inflammatory reaction in the vascular wall and may play an active role in the progression of vascular disease. Human Aortic Smooth Muscle Cells allows to perform in vitro assays in vascular disease research.

SMC are long and thin in structure and arrange around tissues in layers. They do not contain any sarcomeres and few nuclei but Myosin appears scattered throughout the cell. Dense-bodies attach to actin filaments in the muscle sarcoplasm, this prevents the actin molecules moving during contraction. The dense-bodies also connect other smooth muscle cells and appears arranged randomly throughout the fibres.

  • Reference: P10456
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only.
  • Shipping Conditions: Dry Ice