Human Bronchial Epithelial Cells

Reference: P10557

Human Bronchial Epithelial Cells

Human Bronchial Epithelial Cells (HBEpiC) provided by Innoprot are isolated from human healthy bronchi. HBEpiC are cryopreserved at passage one and delivered frozen. Each vial of Human Bronchial Epithelial Cells contains more than 500.000 viable cells. HBEpiC are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Bronchial Epithelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HBEpiC culture.

 

Size/Quantity: 500.000 Cells / vial

820,00

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The respiratory epithelium comprises a mixed population of ciliated, nonciliated, and mucous-secreting cells from proximal to distal airways. The individual characteristics of these cells create not only an effective physical barrier against various noxious substances, but also a highly sophisticated host defense system by producing and releasing a large number of chemical mediators and cytokines. The bronchial epithelium consists of both, the surface epithelial cells and mucus glands. The surface epithelial cells comprise three principle cell types; basal, goblet, and ciliated cells, of which the latter two form a suprabasal columnar structure. They are necessary for mucociliary clearance. Studies using human bronchial epithelial cells (BEpiC) have demonstrated that IL-4 and IL-13 stimulation can modify cellular proliferation, but also ciliary beating, and mucous production. BEpiC proliferation depends in part by EGF receptor signaling. Cultured BEpiC are a useful in vitro model for studying the function and pathophysiology of the bronchial epithelium.

 

 

  • Reference: P10557
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice