Human Bronchial Fibroblasts

Reference: P10563

Human Bronchial Fibroblasts

Human Bronchial Fibroblasts (HBF) provided by Innoprot are isolated from human healthy bronchi and bronchioles. HBF are cryopreserved at passage one and delivered frozen. Each vial of Human Bronchial Fibroblasts contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Bronchial Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HBF culture.

 

Size/Quantity: 500.000 Cells / vial

750,00

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The most abundant cell type in the bronchus is fibroblasts. Human Bronchial Fibroblasts (HBF) display a mesenchymal stem cell phenotype and their principle function is to produce type III collagen, elastin, and proteoglycans of the extracellular matrix. Bronchial fibroblasts play an important role in the repair and remodeling processes following injury. The controlled accumulation of fibroblasts to sites of inflammation is crucial for effective tissue repair after injury. Either inadequate or excessive accumulation of fibroblasts can result in abnormal tissue function. For example, the excess fibroblast proliferation and collagen secretion that occurs from bronchial subepithelial fibrosis can result in airway obstruction and bronchial hyper-responsiveness. HBF cultures provide an in vitro model in the pathophysiological studies of bronchial disorders; such as bronchiectasis, bronchiolitis or bronchopulmonary dysplasia.

  • Reference: P10563
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice