Human Bronchial Smooth Muscle Cells

Reference: P10561

Human Bronchial Smooth Muscle Cells

Human Bronchial Smooth Muscle Cells (HBSMC) provided by Innoprot are isolated from human healthy bronchi and bronchioles. HBSMC are cryopreserved at passage one and delivered frozen. Each vial of Human Bronchial Smooth Muscle Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Bronchial Smooth Muscle Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HBSMC culture.

 

Size/Quantity: 500.000 Cells / vial

650,00

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Airway smooth muscle is fundamental for maintaining airway tone. The specialized ultrastructural features and regulatory mechanisms of airway smooth muscle are vital for normal airway function. Patients with respiratory disorders, such as severe asthma, exhibit the distinguishing feature of increased bronchial smooth muscle mass. The increase in smooth muscle mass is related either to abnormal bronchial smooth muscle cell (BSMC) proliferation or the accumulation of contractile protein. Smooth muscle cell proliferation is an important component of airway remodeling in asthma. It is consequently a target for the development of novel anti-asthma agents. Airway smooth muscle cells express CT-1 and release GM-CSF, RANTES and IL-8 in vitro. In order to develop therapies for asthma, researchers have utilized Human Bronchial Smooth Muscle Cells to elucidate the cellular and molecular mechanisms underlying BSMC proliferation.

  • Reference: P10561
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice