Human Cardiac Myocytes

Reference: P10451

Human Cardiac Myocytes

Human Cardiac Myocytes (HCM) provided by Innoprot are isolated from human healty heart. HCM are cryopreserved just after purification and delivered frozen. Each vial of Human Cardiac Myocytes contains more than 1 million viable cells. HCM are guaranteed to further culture under the conditions provided by Innoprot; however, HCM are not recommended for expanding or long-term cultures since the cells do not proliferate in culture.

Innoprot also offers optimized medium and reagents for maintenance of Human Cardiac Myocytes which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HCM culture.

 

Size/Quantity: 1 million Cells / vial

875,00

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Human Cardiac Myocytes are the most physically energetic cells in the body. They are highly specialized high-oxygen-content cells that house a large number of mitochondria. They occupy as much as 75% of the cardiac mass, but constitute only about one third of the total cell number in the heart. Differentiated cardiac myocytes have little capacity to proliferate; however, hypertrophic growth responds to alpha1-adrenergic stimuli via the Ras/MEK pathway. All cardiac myocytes are capable of spontaneous rhythmic depolarization and repolarization of their membranes. Contraction of cardiac myocytes is myogenic, which is independent of nervous stimulation. There is a complex network of signals in cardiac myocytes regulating the rhythmic pumping of the heart. Cardiac myocyte hypertrophy and apoptosis plays an important role in the loss of contractile function during heart failure. A better understanding of the cardiac signaling network will help reveal the cellular mechanisms leading to cardiac myocyte death.

  • Reference: P10451
  • Size/Quantity: 1x106 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice

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