Human Colonic Microvascular Endothelial Cells

Reference: P10769

Human Colonic Microvascular Endothelial Cells

Human Colonic Microvascular Endothelial Cells (HCoMEC) provided by Innoprot are isolated from human healthy colon. HCoMEC are cryopreserved at passage one and delivered frozen. Each vial of Human Colonic Microvascular Endothelial Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 10 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Colonic Microvascular Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HCoMEC culture.


Size/Quantity: 500.000 Cells / vial


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Endothelial cells lining the microvasculature play a critical “gatekeeper” role in the inflammatory process through their ability to recruit circulating immune cells into tissues and foci of inflammation. Intestinal microvascular endothelial cells exhibit a strong immune response to LPS challenge. It also plays a critical regulatory role in gut inflammation. Pharmacological inhibition of NOS in activated intestinal microvascular endothelial cells resulted in a significant increase in leukocytes binding. Gene expression profile studies reveals that intestinal endothelial cells express biotinidase, which involves in biotin recycling. Human colonic microvascular endothelial cells allow performing systematic analyses of cytokine profiles with regard to mRNA expression and protein secretion.

  • Reference: P10769
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice