Human Hepatic Stellate Cells

Reference: P10653

Human Hepatic Stellate Cells

Human Hepatic Stellate Cells (HHSteC) provided by Innoprot are isolated from human healthy liver. HHSteC are cryopreserved at passage one and delivered frozen. Each vial of Human Hepatic Stellate Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Hepatic Stellate Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HHSteC culture.


Size/Quantity: 500.000 Cells / vial


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Human Hepatic stellate cells (HSteC) are intralobular connective tissue cells presenting myofibroblast-like or lipocyte phenotypes. They participate in the homeostasis of liver extracellular matrix, repair, regeneration, fibrosis and control retinol metabolism, storage and release. Following liver injury, HSteC transform into myofibroblast-like cells; furthermore they are the major source of type I collagen in the fibrotic liver. Beyond these features, HSteC act as regulators of hepatic microcirculation via cell contraction, moreover in disease states, in the pathogenesis of intrahepatic portal hypertension. Proliferation and migration of HSteC and expression of chemokines play roles in the pathogenesis of liver inflammation and fibrogenesis. New insight into the molecular regulation of HSteC activation will lead to therapeutic approaches in treatment of hepatic fibrosis. HSteC could lead to reduced morbidity and mortality in patients with chronic liver injury.

  • Reference: P10653
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice