Human Kidney Fibroblasts

Reference: P10666

Human Kidney Fibroblasts

Human Kidney Fibroblasts (HKF) provided by Innoprot are isolated from human healthy kidney. HKF are cryopreserved at passage one and delivered frozen. Each vial of Human Kidney Fibroblasts contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Kidney Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HKF culture.

 

Size/Quantity: 500.000 Cells / vial

765,00

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As an excretory organ in the urinary system, the kidney greatly influences an individual’s well being by preserving homeostasis through different mechanisms, such as regulating electrolytes, pH, and blood pressure. Human kidney fibroblasts are responsible for the synthesis of collagen I of the extracellular matrix. Also, kidney fibroblasts synthesize erythropoietin, an important glycoprotein hormone that controls the production of red blood cells. They produce prostaglandins, a class of autocrine or paracrine hormones, which help maintain water and electrolyte homeostasis. Renal fibrosis, a disorder that may escalate to chronic kidney disease, is often related with excessive deposition of extracellular matrix. HKF in culture provide a useful in vitro model for studying the relationship between fibroblasts and renal disease. They are also useful tools to stablish in vitro disease models for High Throughput and High Content Screening.

 

 

  • Reference: P10666
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice