Human Myometrial Smooth Muscle Cells

Reference: P10994

Human Myometrial Smooth Muscle Cells

Human Myometrial Smooth Muscle Cells (HMSMC) provided by Innoprot are isolated from human healthy uterus. HMSMC are cryopreserved at passage one and delivered frozen. Each vial of Human Myometrial Smooth Muscle Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Myometrial Smooth Muscle Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HMSMC culture.

 

Size/Quantity: 500.000 Cells / vial

830,00

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Human Myometrial smooth muscle cells (MSMC) are located in the myometrium between the endometrium and the serosa of the uterus. MSMC play role in the stretching of the uterus during pregnancy and are also responsible for uterine contractions during labor. To accommodate the growing embryo, the myometrium expands through smooth muscle cell hypertrophy and hyperplasia. Typically, the uterine myometrium consists of differentiated smooth muscle cells, but in certain pathological conditions, such as uterine leiomyomata, smooth muscle cells in the myometrium proliferate abnormally to form tumors. Studies indicate that platelet-derived growth factor (PDGF) may stimulate MSMC proliferation and consequently may play a role in the formation of leiomyomata. Cultured MSMC are an excellent model to study the physiology of pregnancy and labor; but also the mechanisms that contribute to the development of uterine leiomyomata

Human Myometrial Smooth Muscle Cells are also useful tools to develop disease models for High Throughput and High Content Screening.

 

 

  • Reference: P10994
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice