Human Pericardial Fibroblasts

Reference: P10465

Human Pericardial Fibroblasts

Human Pericardial Fibroblasts (HPcF) provided by Innoprot are isolated from adult healthy pericardial tissue. HPcF are cryopreserved at passage one and delivered frozen. Each vial of Human Pericardial Fibroblasts contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Pericardial Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HPcF culture.


Size/Quantity: 500.000 Cells / vial


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The pericardium is a double-walled sac containing the heart and the roots of the great vessels. The pericardial sac has two layers, a serous layer and a fibrous layer. It encloses the pericardial cavity which contains pericardial fluid. Human Pericardial Fibroblasts (HPcF) are the major cell type of the pericardium. They produce collagens and help form the thin but strong pericardium to serve as a protective sac. It provides structural support and lubrication, and also prevents excessive dilation of the heart. Constrictive Pericarditis involves activation and proliferation of pericardial fibroblasts, collagen and fibrin deposition, chronic inflammation, and scarring, where pericardium hardening eventually prevents the heart from expanding. Associations between fibroblast activation and immunomodulation make Pericardil Fibroblast cultures a useful tool for studying progressive sclerosing pericarditis.



  • Reference: P10465
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice