Human Periodontal Ligament Fibroblasts

Reference: P10867

Human Periodontal Ligament Fibroblasts

Human Periodontal Ligament Fibroblasts (HPLF) provided by Innoprot are isolated from human healthy periodontal tissue. HPLF are cryopreserved at passage one and delivered frozen. Each vial of Human Periodontal Ligament Fibroblasts contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Periodontal Ligament Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HPLF culture.


Size/Quantity: 500.000 Cells / vial


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The periodontal ligament is connective tissue located between the cementum of the teeth and the alveolar bone of the mandibula. It plays an integral role in the maintenance and regeneration of periodontal tissue. Fibroblasts are the responsible for maintaining this tissue. They can be either multipotent or composed of heterogeneous cell populations that differ in their function. Despite the similar morphology with gingival fibroblasts, periodontal ligament fibroblasts (PLF) appear to display distinct functional activities in the maintenance of tissue integrity. PLF produce osteoblast-related extracellular matrix proteins and show higher alkaline phosphatase activity compared with gingival fibroblasts. Human Periodontal Ligament Fibroblasts actively participate in immune and inflammatory events in periodontal disease, such as periodontitis.

  • Reference: P10867
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice