Human Rectal Fibroblasts

Reference: P10777

Human Rectal Fibroblasts

Human Rectal Fibroblasts (HRecF) provided by Innoprot are isolated from human healthy rectum. HRecF are cryopreserved at passage one and delivered frozen. Each vial of Human Rectal Fibroblasts contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Rectal Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HRecF culture.

 

Size/Quantity: 500.000 Cells / vial

765,00

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The human rectum is present in the lower gastrointestinal tract and functions as a temporary storage site for fecal material. Rectal fibroblasts are important structural components of the rectum and involve a number of diseases; such as ulcerative colitis, Crohn’s disease, and rectal cancer. The main functions of fibroblasts are to maintain the structural integrity of connective tissue and also to aid in tissue repair and remodeling. Functional changes to human rectal fibroblasts (HRecF) can impair wound healing and affect epithelial cell proliferation in ulcerative colitis patients. In Crohn’s disease, HRecF respond to intestinal inflammation by proliferating abnormally, which leads to fibrotic scarring. Primary HRecF are useful tools to study the pathophysiology of several disesases; such as rectal cancer, ulcerative colitis, and Crohn’s disease and to help develop therapies for these diseases.

  • Reference: P10777
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice