Human Renal Proximal Tubular Epithelial Cells

Reference: P10662

Human Renal Proximal Tubular Epithelial Cells

Human Renal Proximal Tubular Epithelial Cells (HRPTEpiC) provided by Innoprot are isolated from human healthy kidney. HRPTEpiC are cryopreserved at passage one and delivered frozen. Each vial of Human Renal Proximal Tubular Epithelial Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Renal Proximal Tubular Epithelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HRPTEpiC culture.

 

Size/Quantity: 500.000 Cells / vial

770,00

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Human Renal Proximal Tubular Epithelial Cells (HRPTEpiC) play a crucial role in renal function. They reabsorb nearly all of the glucose and amino acids in the glomerular filtrate, while allowing the secretion in the urine of other substances without nutritional value. HRPTEpiC are located near injury sites in a variety of congenital, metabolic, and inflammatory diseases. They can produce inflammatory mediators such as cytokines and chemokines; and actively participate in acute inflammatory processes by affecting and directing leukocyte chemotaxis via the production of IL-8. PTEpiC express IL-2R alpha and MHC class II antigens during inflammation, after renal transplantation, or in crescentic glomerulonephritis. HRPTEpiC in culture provide a useful in vitro model for studying the relationship between tubular cells and renal disease. They are also useful tools to stablish in vitro disease models for High Throughput and High Content Screening.

 

 

  • Reference: P10662
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice