Human Splenic Endothelial Cells

Reference: P10691

Human Splenic Endothelial Cells

Human Splenic Endothelial Cells (HSEC) provided by Innoprot are isolated from human healthy spleen. HSEC are cryopreserved at passage one and delivered frozen. Each vial of Human Splenic Endothelial Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Splenic Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HSEC culture.


Size/Quantity: 500.000 Cells / vial


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The spleen performs essential functions in the turnover of erythrocytes. It removes erythrocytes, metabolizes hemoglobin, and recycles iron. The spleen also mounts a primary immune response to antigens in the blood and synthesizes antibodies in its white pulp. Human splenic endothelial cells (HSEC), similar to other endothelial cells, constitute the natural interface between the blood and the underlying tissue. Previous studies have demonstrated an intriguing link between splenic endothelial cells, splenic hamartoma and capillary hemangioma. Splenic endothelial cells have also shown a supportive micro-environment for the development of dendritic cells. Furthermore, rapid destruction of young erythrocytes can occur in the spleen due to altered endothelial cell-macrophage interactions. These observations suggest that splenic endothelial cells may play a more compelling role in the mononuclear phagocyte system.



  • Reference: P10691
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice