Human Tenocytes are responsible for the synthesis and maintenance of a mechanically unique connective tissue; endowing them with the ability to resist the high tensile forces subjected to the tendon in vivo. Tenocytes are parto of an extensive three-dimensional network of extracellular matrix components consisting predominantly of collagen type I fibrils (>95% of tendon collagen), but also other types of collagen (type III and type V), proteoglycans, elastin and fibronectin. These tendon-specific matrix components give tendon its resilience and biomechanical stability. Human Tenocytes are useful in vitro models for studying tendon regeneration and repair, cytokine and growth factor effects on tendon; but also specific gene regulation and pathophysiology of tendon disorders. They are also useful tools to stablish in vitro disease models for High Throughput and High Content Screening.
Human Tenocytes (HTC) provided by Innoprot are isolated from human healthy patellar tendon. HTC are cryopreserved at passage one and delivered frozen. Each vial of Human Tenocytes contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.
Innoprot also offers optimized medium and reagents for the growth of Human Tenocytes which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HTC culture.
Size/Quantity: 500.000 Cells / vial