Human Villous Mesenchymal Fibroblasts

Reference: P10959

Human Villous Mesenchymal Fibroblasts

Human Villous Mesenchymal Fibroblasts (HVMF) provided by Innoprot are isolated from human healthy placental villi. HVMF are cryopreserved at passage one and delivered frozen. Each vial of Human Villous Mesenchymal Fibroblasts contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Villous Mesenchymal Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HVMF culture.


Size/Quantity: 500.000 Cells / vial


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Fibroblasts are mesenchymal cells which come from the embryonic mesoderm. Since tissue-specific mesenchymal cells are essential for normal organ development, the villous mesenchymal fibroblasts (VMF) are useful as a model system for studying the cellular mechanisms involved in regulating human placental growth. The VMF lie directly beneath the villous basement membrane; they synthesize HGF, CSF-1, gCSF and IL-6 and play an important role in the regulation of trophoblast growth and function. Studies show that paracrine interaction between placental VMF and the cytotrophoblast in anchoring sites is necessary for stimulating trophoblast infiltration. Human Villous Mesenchymal Fibroblasts are also useful tools to develop disease models for High Throughput and High Content Screening.



  • Reference: P10959
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice