Immortalized Human Kidney Podocytes

Reference: P10669-IM

Immortalized Human Kidney Podocytes

Immortalized Human Kidney Podocytes (IM-HKP) provided by Innoprot have been developed by immortalizing primary human healthy kidney podocytes with SV40 Large T antigen.

Immortalized cells were controlled passaging side by side with the primary cells. Primary cells go into senescence after the 4th passage while the SV40‐tranduced cells go beyond 30 passages.

Each vial of Immortalized Human Kidney Podocytes contains more than 1 million viable cells. Innoprot also offers optimized medium and reagents for the growth of IM-HKP which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro IM-HPK culture.


Size/Quantity: 1 million cells / vial


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Immortalized Human Kidney Podocytes in culture provide a useful in vitro model for studying renal disease. Immortalized Human Kidney Podocytes are also useful tools to stablish in vitro disease models for High Throughput and High Content Screening.

Human Kidney Podocytes play a crucial role in renal function. Podocytes are epithelial cells that cover the outer surfaces of glomerular capillaries, making up the epithelial lining of Bowman’s capsule. This capsule filters the blood, retaining large molecules such as proteins while smaller molecules; such as water, salts, and sugars are filtered as the first step in the formation of urine. Vesicular transport is one of the most relevant processes in this polarized cell type. Its injury is the cause of various forms of kidney disease: the extent of this injury and its reversibility have important implications for treatment and prognosis. Podocytes play a key role in the prevention of proteinuria in the healthy situation. They are important targets of injury in a variety of renal diseases and are important determinants of outcome.


  • Reference: P10669-IM
  • Size/Quantity: 1x106 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice