Rat Renal Mesangial Cells

Reference: P10608

Rat Renal Mesangial Cells

Rat Renal Mesangial Cells (RRMC) provided by Innoprot are isolated from rat kidney. RRMC are cryopreserved at passage one and delivered frozen. Each vial of Rat Renal Mesangial Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 10 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Rat Renal Mesangial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro RRMC culture.

Size/Quantity: 500.000 Cells / vial

335,00

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Renal mesangial cells are perivascular cells located within the central portion of the glomerular tuft between capillary loops. They constitute 30-40% of the total glomerular cell population. They regulate the intraglomerular capillary flow and ultrafiltration surface via mesangial cell contraction and release of growth factors and vasoactive agents. By pinocytosis and phagocytosis, mesangial cells remove local accumulation of macromolecules in the mesangial space. Mesangial cells also synthesize, assemble and control turnover of the mesangial matrix. Overproduction of mesangial cells occurs in various glomerular diseases; such as IgA nephropathy, mesangioproliferative glomerulonephritis, lupus nephritis, glomerulosclerosis and diabetic nephropathy. Such critical involvements suggest rat renal mesangial cells are an ideal model for studying mesangial injury and glomerular functions under both physiological and pathophysiological conditions.

  • Reference: P10608
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice