Red Fluorescent PC-3 Cell Line

Reference: P20315

Red Fluorescent PC-3 Cell Line

Red Fluorescent PC-3 Cell Line (aka VAMPIRO PC-3) has been developed through stable transfection of PC-3 cell line with tFP602. This cell line expresses true-red fluorescent protein gene sequences as free cytoplasmatic proteins. Each vial of cells contains more than 3 million viable cells stably expressing tFP602 with Puromycin resistance gene:

VAMPIRO PC-3 Cell line is ready to use in cell-based assay applications. This stably transfected clonal cell line provides consistent levels of expression, which helps simplify the interpretation of results. Red Fluorescent PC-3 Cell Line also allows to stablish in vitro models for High Throughput and High Content Screening.

950,00

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Red Fluorescent PC-3 Cell Line are suitable for both, in vitro and in vivo experimentation.

 

About PC-3 Cell line:

PC-3 cell line comes from a bone metastasis of a grade IV prostatic adenocarcinoma from a 62-year-ol Caucasian male. These cells do not respond to androgens, glucocorticoids, or epidermal or fibroblast growth factors. PC-3 cells are useful in investigating the biochemical changes in advanced prostatic cancer cells and in assessing their response to chemotherapeutic agents. Moreover, they are useful to create subcutaneous tumors in mice in order to investigate a model of the tumor environment in the context of the organism. Due to their high metastatic potential, these cells are also useful to develop metastasis mouse models.

 

About turboFP602 protein:

TurboFP602 protein is a red shifted variant of the red fluorescent protein TurboRFP from sea anemone Entacmaea quadricolor [Merzlyak et al., 2007]. It possesses true-red fluorescence (excitation/ emission max = 574/ 602 nm) that is optimal for detection via most popular filter sets. TurboFP602 exhibits fast maturation and also high pH stability. TurboFP602 is useful for applications where fast appearance of bright fluorescence is crucial. It is also useful for cell and organelle labeling and tracking the promoter activity.

  • Reference: P20315
  • Size/Quantity: 3x106 cells / vial
  • Resistance Gene: Puromycin
  • Red Fluorescent Protein: tFP602 (excitation/emission maxima at 574/602 nm, respectively)
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice