A novel family of SH-SY5Y cell lines have been developed through stable transfection with different fluorescent isoforms of tau protein and mutants.
Each cell line is stably‐transfected and it is ready to use in cell‐based assay applications. These stably transfected cell lines provide consistent levels of expression, which helps to simplify the interpretation of the results. These cell lines are intended to be used as “in vitro” models for tau research studies.
Green Fluorescent U2OS Cell Line (aka LINTERNA U2OS) has been developed through stable transfection of U2OS cell line with tGFP. This cell line expresses green fluorescent protein gene sequences as free cytoplasmatic proteins. Each vial of cells contains more than 3 million viable cells stably expressing tGFP with puromycin resistance gene:
LINTERNA U2OS Cell line is ready to use in cell-based assay applications. This stably transfected clonal cell line provides consistent levels of expression, which helps simplify the interpretation of results. Green Fluorescent U2OS Cell Line also allows to stablish in vitro models for HIgh Throughput and High Content Screening.
A novel HEK293 Cell line has been developed through stable transfectionof an expression vector for a fusion protein of turboGFP and human Androgen Receptor. The resultant cell line allows to monitor the dynamics of the hormone/receptor complex in living cells and to assay for compounds inducing tGFP-hAR nuclear translocation and formation of nuclear foci.
Innoprot hAR nuclear translocation Cell Line has been designed to assay compounds or analyze stimuli for their ability to modulate androgen receptor nuclear translocation process and quantifying the fluorescence distribution inside the cells. This highly reproducible assay allows monitoring androgen receptor nuclear translocation process in High Content Analysis and fluorescence microscope applications.
Each vial of hAR Nuclear Translocation HEK293 Cell Line contains 3 million cells and Innoprot provides two vials of cells with each order. It is guaranteed that these cells will expand in more than 30 passages following the cell culture manual.
HematoGroW Medium Kit is a complete medium designed for short-term maintenance of hematopoietic cells in vitro. Each HematoGroW Medium Kit consists of the next components:
Hepatocyte Medium Kit is a complete medium designed for optimal growth of normal primary hepatocytes in vitro. Each Hepatocyte Medium Kit consists of the next components:
A novel HEK293 Cell line has been developed through stable transfectionof an expression vector for a fusion protein of turboGFP and human Glucocorticoid Receptor. The resultant cell line allows to monitor the dynamics of the hormone/receptor complex in living cells and to assay for compounds inducing tGFP-hGR nuclear translocation and formation of nuclear foci.
Innoprot GR nuclear translocation Cell Line has been designed to assay compounds or analyze stimuli for their ability to modulate glucocorticoid receptor nuclear translocation process and quantifying the fluorescence distribution inside the cells. This highly reproducible assay allows monitoring glucocorticoid receptor nuclear translocation process in High Content Analysis and fluorescence microscope applications.
Each vial of hGR Nuclear Translocation HEK293 Cell Line contains 3 million cells and Innoprot provides two vials of cells with each order. It is guaranteed that these cells will expand in more than 30 passages following the cell culture manual.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker 5-HT2A Serotonin Receptor Cell Line contains U2OS cells stably expressing 5-HT2A Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker 5-HT2A Serotonin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate 5-HT2A receptor. When a ligand binds to the 5-HT2A receptor, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker 5-HT2A Serotonin Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with 5-HT. The high reproducibility of this assay allows monitoring 5-HT2A Receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker 5-HT2C Serotonin Receptor Cell Line contains U2OS cells stably expressing 5-HT2C Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker 5-HT2C Serotonin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate 5-HT2C receptor. When a ligand binds to the 5-HT2C receptor, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker 5-HT2C Serotonin Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with 5-HT. The high reproducibility of this assay allows monitoring 5-HT2C Receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker Adenosine A2A Receptor Cell Line contains HEK293 cells stably expressing ADORA2A with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker ADORA2A Cell Line allows to assay compounds, or analyze their capability to modulate ADORA2A. When a ligand binds to the ADORA2A, it activates a G protein, which in turn, triggers a cellular response mediated by cAMP. HiTSeeker ADORA2A cell line has been validated measuring cAMP concentration changes in the cytosol upon activation with NECA. The high reproducibility of this assay allows monitoring ADORA2A receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker Adenosine A2B Receptor Cell Line contains HEK293 cells stably expressing ADORA2B with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker ADORA2B Cell Line allows to assay compounds, or analyze their capability to modulate ADORA2B. When a ligand binds to the ADORA2B, it activates a G protein, which in turn, triggers a cellular response mediated by cAMP. HiTSeeker ADORA2B cell line has been validated measuring cAMP concentration changes in the cytosol upon activation with NECA. The high reproducibility of this assay allows monitoring ADORA2B receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker alpha1A Adrenergic Receptor Cell Line contains U2OS cells stably expressing ADRA1A with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker ADRA1A Cell Line allows to assay compounds, or analyze their capability to modulate ADRA1A. When a ligand binds to the ADRA1A, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker ADRA1A cell line has been validated measuring calcium concentration changes in the cytosol upon activation with epinephrine. The high reproducibility of this assay allows monitoring ADRA1A receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker alpha1B Adrenergic Receptor Cell Line contains U2OS cells stably expressing ADRA1B with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker ADRA1B Cell Line allows to assay compounds, or analyze their capability to modulate ADRA1B. When a ligand binds to the ADRA1B, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker ADRA1B cell line has been validated measuring calcium concentration changes in the cytosol upon activation with epinephrine. The high reproducibility of this assay allows monitoring ADRA1B receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker AVPR1A Cell Line contains HEK293 cells stably expressing AVPR1A with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker AVPR1A Cell Line allows to assay compounds, or analyze their capability to modulate AVPR1A. When a ligand binds to the AVPR1A, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker AVPR1A cell line has been validated measuring calcium concentration changes in the cytosol upon activation with AVP. The high reproducibility of this assay allows monitoring AVPR1A receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker BB2 Bombesin Receptor Cell Line contains U2OS cells stably expressing BB2 Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker BB2 Bombesin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate BB2 receptor. When a ligand binds to the BB2 receptor, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker BB2 Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with GRP. The high reproducibility of this assay allows monitoring BB2 receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker beta-2 adrenergic receptor Cell Line contains HEK293 cells stably expressing ADRB2 with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker ADRB2 Cell Line allows to assay compounds, or analyze their capability to modulate ADRB2. When a ligand binds to the ADRB2, it activates a G protein, which in turn, triggers a cellular response mediated by cAMP. HiTSeeker ADRB2 cell line has been validated measuring cAMP concentration changes in the cytosol upon activation with Isoproterenol. The high reproducibility of this assay allows monitoring ADRB2 receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker beta-3 adrenergic receptor Cell Line contains HEK293 cells stably expressing ADRB3 with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker ADRB3 Cell Line allows to assay compounds, or analyze their capability to modulate ADRB3. When a ligand binds to the ADRB3, it activates a G protein, which in turn, triggers a cellular response mediated by cAMP. HiTSeeker ADRB3 cell line has been validated measuring cAMP concentration changes in the cytosol upon activation with isoproterenol. The high reproducibility of this assay allows monitoring ADRB3 receptor activation process in High Throughput Screening.
HiTSeeker beta-2 adrenergic receptor Cell Line 
