Bradykinin Receptors

B1 Bradykinin Receptor Internalization Assay

B1 Bradykinin Receptor Internalization Assay from Innoprot allows to assay compounds, or analyze their capability to modulate BDKRB1 activation and the following redistribution process inside the cells. When a ligand binds to the BDKRB1, it activates a G protein, which internalizes in big and high intensity vesicles. This assay has been validated measuring Fluorescent BDKRB1…

B2 Bradykinin Receptor Assay

Bradykinin Receptor B2 Assay from Innoprot provides the analysis of both signalling pathways involving GPCR activation; G protein by Calcium flux and β-arrestin recruitment using Nomad multiplex technology. The primary transduction mechanism involves Gq/G11 family transducers, so we measure Ca2+ flux in combination with β-arrestin recruitment in this assay. The bradykinin receptor family is a group…