FP Prostanoid Receptor Assay (PTGFR) from Innoprot allows to assay compounds, or analyze their capability to modulate PTGFR. When a ligand binds to the PTGFR, it activates a G protein; which in turn, triggers a cellular response mediated by calcium. The binding of an agonist to PTGFR induces mobilization of intracellular calcium and also activation…
EP4 Prostanoid Receptor Assay from Innoprot measures PTGER4 receptor activation using HTRF technology. PTGER4 Receptor signaling occurs via adenylate cyclase stimulation through trimeric Gs proteins, increasing cAMP, and also downstream L-type calcium channel interaction. In this assay, we measure the receptor activation/inhibition by cAMP accumulation using HTRF technology. The high reproducibility of this assay allows…
EP2 Prostanoid Receptor Assay from Innoprot measures PTGER2 receptor activation using HTRF technology. PTGER2 Receptor signaling occurs via adenylate cyclase stimulation through trimeric Gs proteins, increasing cAMP, and also downstream L-type calcium channel interaction. In this assay, we measure the receptor activation/inhibition by cAMP accumulation using HTRF technology. The high reproducibility of this assay allows…
EP1 Prostanoid Receptor Assay (PTGER1) from Innoprot allows to assay compounds, or analyze their capability to modulate PTGER1. When a ligand binds to the PTGER1, it activates a G protein; which in turn, triggers a cellular response mediated by calcium. The binding of an agonist to PTGER1 induces mobilization of intracellular calcium and also activation…