VPAC2 Receptor Assay (VIPR2) from Innoprot measures VIPR2 activation using Nomad Biosensors technology. VPAC2 Receptor signaling occurs via adenylate cyclase stimulation through trimeric Gs proteins, increasing cAMP, and downstream L-type calcium channel interaction. In this assay, we measure the receptor activation/inhibition by cAMP accumulation using cAMP-Nomad Biosensor. The high reproducibility of this assay allows monitoring…
VPAC1 Receptor Assay (VIPR1) from Innoprot measures VIPR1 activation using Nomad Biosensors technology. VPAC1 Receptor signaling occurs via adenylate cyclase stimulation through trimeric Gs proteins, increasing cAMP, and downstream L-type calcium channel interaction. In this assay, we measure the receptor activation/inhibition by cAMP accumulation using cAMP-Nomad Biosensor. The high reproducibility of this assay allows monitoring…
Urotensin II Receptor Assay (UTS2R) from Innoprot allows to assay compounds, or analyze their capability to modulate UTS2R. When a ligand binds to the UTS2R, it activates a G protein; which in turn, triggers a cellular response mediated by calcium. The binding of an agonist to UTS2R induces mobilization of intracellular calcium and also activation…
NK3 Tachykinin Receptor Assay (TACR3) from Innoprot allows to assay compounds, or analyze their capability to modulate TACR3. When a ligand binds to the TACR3, it activates a G protein; which in turn, triggers a cellular response mediated by calcium. The binding of an agonist to TACR3 induces mobilization of intracellular calcium and also activation…
NK1 Tachykinin Receptor Assay (TACR1) from Innoprot allows to assay compounds, or analyze their capability to modulate TACR1. When a ligand binds to the TACR1, it activates a G protein; which in turn, triggers a cellular response mediated by calcium. The binding of an agonist to TACR1 induces mobilization of intracellular calcium and also activation…
SST5 Somatostatin Receptor Internalization Assay from Innoprot allows to assay compounds, or analyze their capability to modulate SST5 Somatostatin Receptor (SSTR5) activation and the following redistribution process inside the cells. When a ligand binds to the SSTR5, it activates a G protein, which internalizes in big and high intensity vesicles. This assay has been validated…
SST3 Somatostatin Receptor Internalization Assay from Innoprot allows to assay compounds, or analyze their capability to modulate SST3 Somatostatin Receptor (SSTR3) activation and the following redistribution process inside the cells. When a ligand binds to the SSTR3, it activates a G protein, which internalizes in big and high intensity vesicles. This assay has been validated…
SST2 Somatostatin Receptor Internalization Assay from Innoprot allows to assay compounds, or analyze their capability to modulate SST2 Somatostatin Receptor (SSTR2) activation and the following redistribution process inside the cells. When a ligand binds to the SSTR2, it activates a G protein, which internalizes in big and high intensity vesicles. This assay has been validated…
5-HT2C Serotonin Receptor Assay (HTR2C) from Innoprot allows to assay compounds, or analyze their capability to modulate HTR2C. When a ligand binds to the HTR2C, it activates a G protein; which in turn, triggers a cellular response mediated by calcium. The binding of an agonist to HTR2C induces mobilization of intracellular calcium and also activation…