The beta-3 adrenergic receptor (β3 adrenoceptor); also known as ADRB3, is a cell membrane-spanning beta-adrenergic receptor. beta3 adrenoceptor Assay (ADRB3) from Innoprot allows the measurement of ADRB3 receptor activation using Nomad biosensors technology. beta3 Adrenoceptor signaling occurs via adenylate cyclase stimulation through trimeric Gs protein, increasing cAMP, and downstream L-type calcium channel interaction. cAMP-Nomad Biosensor measures the receptor activation by cAMP accumulation.