Lysophospholipid (S1P) receptors

S1P3 Lysophospholipid Receptor Assay

S1P3 Lysophospholipid Receptor Assay (S1P3R) from Innoprot provides the analysis of both signalling pathways involving S1P3R activation; G Protein by the analysis of Gi/Go activation and also β-arrestin recruitment using Nomad multiplex technology. When an agonist binds to S1P3R, it activates Gi/Go, which in turn, triggers a cellular response involving PKA activation. In this assay…

S1P₁ Lysophospholipid Receptor Internalization Assay

S1P1 Lysophospholipid Receptor Internalization Assay from Innoprot allows to assay compounds, or analyze their capability to modulate S1P1 receptor activation and the following redistribution process inside the cells. When a ligand binds to the S1P1R, it activates a G protein, which internalizes in big and high intensity vesicles. This assay has been validated measuring Fluorescent…