EP4 Prostanoid Receptor Assay from Innoprot measures PTGER4 receptor activation using HTRF technology. PTGER4 Receptor signaling occurs via adenylate cyclase stimulation through trimeric Gs proteins, increasing cAMP, and also downstream L-type calcium channel interaction.
In this assay, we measure the receptor activation/inhibition by cAMP accumulation using HTRF technology. The high reproducibility of this assay allows monitoring EP4 Prostanoid Receptor Assay activation process in living cells.
Click HERE to know more about EP4 receptor.