Delta Opioid Receptor Internalization Assay from Innoprot allows to assay compounds, or analyze their capability to modulate Delta Opioid receptor (OPRD1) activation and the following redistribution process inside the cells. When a ligand binds to the OPRD1, it activates a G protein, which internalizes in big and high intensity vesicles.
This assay has been validated measuring Fluorescent OPRD1 redistribution by increase of fluorescence surrounding the nuclei using image analysis algorithms. The high reproducibility of this assay allows monitoring Delta Opioid Receptor redistribution process in High Throughput Screening.
Receptor Information: Delta Opioid Receptor
Assay: Opioid Receptors