Human Bladder Smooth Muscle Cells

Reference: P10951

Human Bladder Smooth Muscle Cells

Human Bladder Smooth Muscle Cells (HBdSMC) provided by Innoprot are isolated from human healthy bladder. HBdSMC are cryopreserved at passage one and delivered frozen. Each vial of Human Bladder Smooth Muscle Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Bladder Smooth Muscle Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HBdSMC culture.


Size/Quantity: 500.000 Cells / vial


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The urinary bladder is a hollow organ which comprises mainly of smooth muscle cells (SMC). The relaxation and contraction of urinary bladder smooth muscle allows the bladder to store and void urine, respectively. Phenotypic modulation of bladder SMC and the expression of inducible nitric oxide synthase are related with various pathological conditions, including bladder dysfunction. Hypoxia inhibits human bladder SMC proliferation upregulating also survival factors such as HIF1 alpha and VEGF. The secretory phenotype of the bladder SMC extracellular matrix depends on the frequency of mechanical deformation experienced by these cells. SMC proliferation is a major contributing factor to the development and progression of a variety of diseases. As a result, understanding SMC changes during the genesis and maintenance of disease is vital to the development of therapeutic approaches. Human Bladder Smooth Muscle Cells are also useful tools to develop disease models for High Throughput and High Content Screening.

  • Reference: P10951
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice