Human Colonic Smooth Muscle Cells

Reference: P10752

Human Colonic Smooth Muscle Cells

Human Colonic Smooth Muscle Cells (HCoSMC) provided by Innoprot are isolated from human healthy colon. HCoSMC are cryopreserved at passage one and delivered frozen. Each vial of Human Colonic Smooth Muscle Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Colonic Smooth Muscle Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HCoSMC culture.


Size/Quantity: 500.000 Cells / vial


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Smooth muscle contraction is the fundamental event in gastrointestinal motion. Inflammation of the human intestine causes increased levels of smooth muscle-specific actin, which in turn promotes the thickening of the smooth muscle layers. The increased smooth muscle actin may affect force production and further demonstrates the plasticity of HCoSMC in the inflamed intestine. Studies also show that human intestinal smooth muscle cells respond to IL-1beta and TNF-alpha stimulation by releasing IL-6. It may significantly contribute to the overall systemic inflammatory response. Human colonic smooth muscle cells (HCoSMC) possess a different subtype of somatostatin receptor from gastric smooth muscle cells. HCoSMC makes it more feasible to study the contractile and proliferative responses of human colonic smooth muscle.

  • Reference: P10752
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice