Human Dermal Microvascular Endothelial Cells

Reference: P10861

Human Dermal Microvascular Endothelial Cells

Human Dermal Microvascular Endothelial cells (HDMEC) provided by Innoprot are isolated from human healthy dermal tissue. HDMEC are cryopreserved at passage one and delivered frozen. Each vial of Human Dermal Microvascular Endotheilal Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Dermal Microvascular Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HDMEC culture.


Size/Quantity: 500.000 Cells / vial


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Blood vessels of the skin contains both, cellular and non-cellular elements. The predominant cell type in all skin blood vessels is endothelial cells. Endothelial cells form the interface between intravascular and extravascular compartments. They serve as a selective barrier for the diffusion of cells and macromolecules between these two compartments. While endothelial cells lining blood vessels of the skin share features of endothelial cells elsewhere in the body, they also exhibit several skin specific characteristics. Human Dermal Microvascular Endothelial Cells provide an invaluable tool for understanding DMEC physiological and pathophysiological relevance in dermal function.

HDMEC actively participate in a variety of physiological processes including wound healing, control of hemostasis or temperature regulation. Via signaling pathways controlling cell proliferation, quiescence, apoptosis, and senescence, the endothelial lining of blood vessels shows remarkable phenotypic and functional heterogeneity, which in turn allows the cutaneous microvasculature to be in a dynamic balance between maintenance and remodeling.

  • Reference: P10861
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice