Human Ovarian Fibroblasts

Reference: P10983

Human Ovarian Fibroblasts

Human Ovarian Fibroblasts (HOF) provided by Innoprot are isolated from human healthy ovary. HOF are cryopreserved at passage one and delivered frozen. Each vial of Human Ovarian Fibroblasts contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Ovarian Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HOF culture.


Size/Quantity: 500.000 Cells / vial


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Fibroblasts are mesenchymal cells which came from the embryonic mesoderm. They synthesize components of the extracellular matrix, maintain the structural integrity of connective tissues, and actively participate in wound healing. Ovarian cancer cells induce normal ovarian fibroblasts to secrete a variety of peptides, such as growth factors, chemokines, collagens, and matrix-modifying enzymes to establish a pro-tumorigenic, anti-immunogenic niche for cancer progression and metastasis. These results suggest that fibroblasts play a stimulatory functional role in cancer development and invasive behavior. Human ovarian fibroblasts will provide an in vitro model in the pathophysiological studies of ovarian diseases. They are also useful tools to stablish in vitro disease models for High Throughput and High Content Screening.

  • Reference: P10983
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice