Subtotal: 0,00€
The IL6R CHO-K1 cell line from Innoprot has been developed by stable transfection with a human Interleukin 6 Receptor (IL6R, a.k.a. CD126) protein expression plasmid. IL6R CHO-K1 cell line provides consistent levels of expression of human IL6R protein in cells surface. Each vial of cells contains more than 3 million viable cells stably expressing IL6R with hygromycin resistance gene.
IL6R CHO-K1 Cell line is ready to use in cell-based assay applications, such as Screening for IL6 antagonists. This stably transfected clonal cell line provides consistent levels of expression, which helps simplify the interpretation of results. IL6R CHO-K1 Cell line also allow to stablish in vitro models for HIgh Throughput and High Content Screening.
5.250,00€
Interleukin-6 (IL-6), a.k.a. CD126, is an important member of the cytokine network and plays a central role in inflammation. In the classical signal transduction pathway, IL-6 binds to its receptor IL-6R to form a complex, and then binds to the membrane protein gp130 to initiate intracellular signal transduction.
COVID19: Antagonists for IL6 could be a possible treatment for severe COVID19 patients with high levels of IL-6.
