Immortalized Human Pancreatic Stromal Cell Line

Reference: P10472-IM

2.085,00€

Immortalized Human Pancreatic Stromal Cells (IM-HPanSC) provided by Innoprot have been developed by immortalizing primary human pancreatic stromal cells with SV40 Large T antigen.

Immortalized cells were controlled passaging side by side with the primary cells. Primary cells go into senescence after the 3th passage while the SV40‐tranduced cells go beyond 30 passages.

Each vial of IM-HPanSC contains more than 1 million viable cells. Innoprot also offers optimized medium and reagents for the growth of IM-HPanSC which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro IM-HPanSC culture.

Size/Quantity: 1 million cells / vial

Mesenchymal stromal cells (MSCs) are heterogeneous group of cells with multipotent capability. Many reports suggest that MSCs reside in almost all tissues and organs. Pancreatic stem cells are of great clinical interest due to their potential role in treatment of diabetes mellitus (DM). Pancreatic Stromal Cells are also able to differentiate into pancreatic endocrine lineage cells. MSC transplantation has shown promising results in treatment of diseases such as diabetes, autoimmune diseases, brain repair, and blood malignancies. Immortalized Human Pancreatic Stromal Cell Line is a useful tool to understand the highly integrated balance between proliferation, differentiation, and cell death. This cell line also allow to stablish in vitro models for HIgh Throughput and High Content Screening.