Red Fluorescent B16-F10 Cell Line are suitable for both, in vitro and in vivo experimentation.
About B16-F10 Cell line:
B16F10 cell line is a high metastatic variant of the murine B16 mouse melanoma, from C57BL/6 (H-2b) mouse strain origin. This cell line is a mixture of both, adherent spindle and epithelial-like cells. B16F10 cell line is a well-established model for metastasis and it is applicable for the study of experimental cancer therapies.
Melanoma tumors express different tumor-associated antigens, which usually induce weak immune responses of short duration. Expression of both tumor-associated antigens p53 and TRP2 by melanoma cells raises the possibility of simultaneously targeting more than one antigen in a therapeutic vaccine.
About turboFP602 protein:
TurboFP602 protein is a red shifted variant of the red fluorescent protein TurboRFP from sea anemone Entacmaea quadricolor [Merzlyak et al., 2007]. It possesses true-red fluorescence (excitation/ emission max = 574/ 602 nm) that is optimal for detection via most popular filter sets. TurboFP602 exhibits fast maturation and also high pH stability. TurboFP602 is useful for applications where fast appearance of bright fluorescence is crucial. It is also useful for cell and organelle labeling and tracking the promoter activity.