Red Fluorescent PC-3 Cell Line

Red Fluorescent PC-3 Cell Line are suitable for both, in vitro and in vivo experimentation.   About PC-3 Cell line: PC-3 cell line comes from a bone metastasis of a grade IV prostatic adenocarcinoma from a 62-year-ol Caucasian male. These cells do not respond to androgens, glucocorticoids, or epidermal or fibroblast growth factors. PC-3 cells are useful in investigating the biochemical changes in advanced prostatic cancer cells and in assessing their response to chemotherapeutic agents. Moreover, they are useful to create subcutaneous tumors in mice in order to investigate a model of the tumor environment in the context of the organism. Due to their high metastatic potential, these cells are also useful to develop metastasis mouse models.   About turboFP602 protein: TurboFP602 protein is a red shifted variant of the red fluorescent protein TurboRFP from sea anemone Entacmaea quadricolor [Merzlyak et al., 2007]. It possesses true-red fluorescence (excitation/ emission max = 574/ 602 nm) that is optimal for detection via most popular filter sets. TurboFP602 exhibits fast maturation and also high pH stability. TurboFP602 is useful for applications where fast appearance of bright fluorescence is crucial. It is also useful for cell and organelle labeling and tracking the promoter activity.