Green Fluorescent ACE2 Cell Line

Reference: P30903

3.500,00€

Green Fluorescent ACE2 cell line from Innoprot has been developed stably transfecting HEK293 cell line with a angiotensin I converting enzyme 2 (ACE2) protein expression plasmid tagged to tGFP. ACE2-tGFP HEK293 cell line provides consistent levels of expression of fluroescent human ACE2 protein in cells surface. Each vial of cells contains more than 3 million viable cells stably expressing ACE2-TGFP with puromycin resistance gene.

ACE2-tGFP HEK293 Cell line is ready to use in cell-based assay applications, such as Screening for ACE2 inhibitors. This stably transfected clonal cell line provides consistent levels of expression, which helps simplify the interpretation of results. ACE2-tGFP HEK293 Cell line also allow to stablish in vitro models for High Throughput and High Content Screening.

Green Fluorescent ACE2 cell line from Innoprot stable expresses ACE2 tagged to tGFP. Angiotensin I converting enzyme 2, a.k.a. ACE2, is a carboxypeptidase that potently degrades angiotensin II to angiotensin 1–7. It also plays a key role in the renin-angiotensin system (RAS). The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus). Green Fluorescent ACE2 cell line allows the study of SARS-CoV-2 spike/ACE2 interaction in cell-based assays. More information about ACE2.

Reference: P30903
Size/Quantity: 3x10⁶ cells / vial
Resistance Gene: Puromycin
Product Use: For research use only
Shipping Conditions: Dry Ice

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