Lysophosphatidic acid (LPA; 1- or 2-acyl-sn-glycerol-3-phosphate) is a phospholipid that plays roles in numerous normal physiological and pathological processes; such as brain development, blood vessel formation, embryo implantation, hair growth, neuropathic pain, lung fibrosis and colon cancer. Among the LPA receptors, LPA3 is unique in that a specific form of LPA (2-acyl LPA with unsaturated fatty acids) activates it. It is also present in a limited number of tissues such as the reproductive organs. LPA3-mediated LPA signaling is essential for proper embryo implantation. HiTSeeker LPA3 Lysophospholipid Receptor Cell Line from Innoprot allows the measurement of the activity and potency of ligands; such as LPA.
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