Human Renal Mesangial Cells

Reference: P10661

Human Renal Mesangial Cells

Human Renal Mesangial Cells (HRMC) provided by Innoprot are isolated from human healthy kidney. HRMC are cryopreserved at passage one and delivered frozen. Each vial of Human Renal Mesangial Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Renal Mesangial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HRMC culture.

 

Size/Quantity: 500.000 Cells / vial

685,00

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Renal mesangial cells are perivascular cells present within the central portion of the glomerular tuft between capillary loops. They have a variety of functions including synthesis and assembly of the mesangial matrix, endocytosis and processing of plasma macromolecules. Human Renal Mesangial Cells (HRMC) control of glomerular hemodynamics via mesangial cell contraction or release of vasoactive hormones. HRMC also synthesize, assemble and control turnover of the mesangial matrix. Matrix overproduction of mesangial cells occurs in various glomerular diseases, such as IgA nephropathy, mesangioproliferative glomerulonephritis, lupus nephritis, glomerulosclerosis and diabetic nephropathy. Such critical involvements suggest renal mesangial cells are an ideal model for studying mesangial injury and glomerular functions under both; physiological and pathophysiological conditions. They are also useful tools to stablish in vitro disease models for High Throughput and High Content Screening.

 

 

  • Reference: P10661
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice