Human Villous Trophoblasts

Reference: P10958

Human Villous Trophoblasts

Human Villous Trophoblasts (HVT) provided by Innoprot are isolated from human placental villi. HVT are cryopreserved at passage one and delivered frozen. Each vial of Human Villous Trophoblasts contains more than 1 million viable cells. They are guaranteed to further culture under the conditions provided in the technical sheet; however, HVT are not recommended for expanding or long-term cultures since the cells do not proliferate in regular culture.

Innoprot also offers optimized medium and reagents for the growth of Human Villous Trophoblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HVT culture.

 

Size/Quantity: 1 million cells / vial

825,00

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The trophoblast begins at the outer covering of the early blastocyst. They provide the route of nourishment between the maternal endometrium and the developing embryo. The trophoblast adhesion to the uterine wall is the requisite first step of implantation and, subsequently, placentation. Human villous trophoblasts (HVT) covering the villi of the placenta provide the surface for the exchange of oxygen and nutrients with the maternal circulation. They synthesize and release chorionic gonadotropin, placental lactogen and angiogenin and express CXCR4, CCR5 and also prolactin gene family. They acquire CCR1 as they differentiate to an invasive phenotype at the villous-anchoring sites. The features of HVT make them an ideal genetic platform to study cell differentiation and organogenesis. They are also useful tools to develop disease models for High Throughput and High Content Screening.

 

 

  • Reference: P10958
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice