Red Fluorescent Immortalized Human Microglia

Reference: P10354-IM-tFP602

Red Fluorescent Immortalized Human Microglia

Red Fluorescent Immortalized Human Microglia (IM-HM-tFP602) provided by Innoprot have been developed by immortalizing primary human microglia with SV40 Large T antigen and stably transfected with tFP602.

Immortalized cells were controlled passaging side by side with the primary cells. These primary cells go into senescence after the 2nd passage while the SV40‐tranduced cells go beyond 30 passages.

Each vial of Red Fluorescent Immortalized Human Microglia contains more than 1 million viable cells. Innoprot also offers optimized medium and reagents for the growth of IM-HM-tFP602 which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro IM-HM-tFP602 culture.


Size/Quantity: 1 million cells / vial


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About HM:

Microglia is an important integral component of the neuro-glial cell network. They are present in the brain parenchyma from the early stage of development to the mature state. Microglia play an important role in brain immune surveillance. They can present antigens in the molecular context of MHC class II expression to CD-4 positive T cells. They are also capable of Fc-mediated phagocytosis, and share many common antigens with hemopoietic and tissue macrophages. Upon activation, they act as brain macrophages to clear tissue debris, damaged cells, or microbes when programmed cell death occurs during brain development or when the CNS is injured. Immortalized Human Microglia Cell Line also allow to stablish in vitro models for HIgh Throughput and High Content Screening.


About turboFP602 protein:

TurboFP602 protein is a red shifted variant of the red fluorescent protein TurboRFP from sea anemone Entacmaea quadricolor [Merzlyak et al., 2007]. It possesses true-red fluorescence (excitation/ emission max = 574/ 602 nm) that is optimal for detection via most popular filter sets. TurboFP602 exhibits fast maturation and also high pH stability. TurboFP602 is useful for applications where fast appearance of bright fluorescence is crucial. It is also useful for cell and organelle labeling and tracking the promoter activity.

  • Reference: P10354-IM-tFP602
  • Size/Quantity: 1x106 cells / vial
  • Red Fluorescent Protein: tFP602 (excitation/emission maxima at 574/602 nm, respectively)
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice